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Vibration LED Derma Roller

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China Derma Roller Manufaturer Microneedle for Wholesale

P2002








Feature:



Anti-Hair Removal, Anti-Puffiness, Blood Vessels Removal, Breast Enhancers, Cellulite Reduction, Dark Circles, Moisturizer, Pigment Removal, Skin Rejuvenation, Weight Loss, Whitening, Wrinkle Remover



Size: 0.2mm, 0.25mm, 0.3mm, 0.5mm, 1.0mm, 1.5mm, 2.0mm, 2.5mm, 3.0mm



China Derma Roller Manufaturer Microneedle for Wholesale

What is a micro-needle technology

Transdermal drug delivery is limited by the extraordinary barrier properties of the stratum corneum, the outer 10-15 mm of skin. Conventional needles inserted across this barrier and into deeper tissue effectively deliver drug, but can lead to infection and cause pain, thereby reducing patient compliance.

 

Advantages of Microneedles

  1. The major advantage of microneedles over traditional needles is, when it is inserted into the skin it does not pass the stratum corneum, which is the outer 10-15 μm of the skin.5 Conventional needles which do pass this layer of skin may effectively transmit the drug but may lead to infection and pain. As for microneedles they can be fabricated to be long enough to penetrate the stratum corneum, but short enough not to puncture nerve endings. Thus reduces the chances of pain, infection, or injury.
  2.  By fabricating these needles on a silicon substrate because of their small size, thousands of needles can be fabricated on a single wafer. This leads to high accuracy, good reproducibility, and a moderate fabrication cost.
  3. Hollow like hypodermic needle; solid—increase permeability by poking holes in skin, rub drug over area, or coat needles with drug .
  4. Arrays of hollow needles could be used to continuously carry drugs into the body using simple diffusion or a pump system.
  5. Hollow microneedles could be used to remove fluid from the body for analysis – such as blood glucose measurements – and to then supply microliter volumes of insulin or other drug as required .
  6. Immunization programs in developing countries, or mass vaccination or administration of antidotes in bioterrorism incidents, could be applied with minimal medical training.
  7. Very small microneedles could provide highly targeted drug administration to individual cells.
  8. These are capable of very accurate dosing, complex release patterns, local delivery and biological drug stability enhancement by storing in a micro volume that can be precisely controlled.

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